Crohn's Disease Treatments Lexington KY

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Dr.Harohalli Shashidhar
(859) 323-5481
740 S Limestone
Lexington, KY
Trevor Anthony Winter
(859) 323-5981
740 S Limestone
Lexington, KY
Donald Denby, MR
270-443-8285
2605 Kentucky Avenue Suite 202,
Lexington, KY
Trevor Winter, MR
859-323-7566
3512 Westmont Circle,
Lexington, KY
Jeffery S Gilbert, MD
859-323-8544
800 Rose Street,
Lexington, KY
Nicholas J Nickl, MD
606-323-5575
400 Dudley Rd,
Lexington, KY
Alvaro G Koch, MD
859-323-6017
800 Rose Street MN 649,
Lexington, KY
Jay Perman
(859) 323-5481
740 S Limestone
Lexington, KY
Nicholas J Nickl III, MD
859-323-5575
800 Rose St Rm Mn654 Gi Div
Lexington, KY
Paul Mandelstam, MD
859-233-4511
University Of Ky Dept Med
Lexington, KY
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Is a Cure for Crohn's Disease on the Way?

Crohn's disease is an inflammatory bowel disease (IBD) that causes inflammation in the lining of your digestive tract that spreads deep into the layers of the affected bowel tissue. Like ulcerative colitis (another common IBD), Crohn's disease can be both painful and debilitating—causing severe diarrhea, stomach pain, cramping, and even malnutrition.

Although there is no known medical cure for Crohn's disease yet, the discovery of a gene linked to a cellular receptor for interleukin-23 (IL-23), a protein involved in the immunity and the inflammatory process, may pave the way to help understand how to prevent the disease from occurring.

In the meantime, there are effective therapies available to reduce the signs and symptoms of the disease and even put it in long-term remission.

The exact cause of Crohn's disease is unknown, but researchers believe that a number of factors, including heredity and a malfunctioning immune system, play a role in the development of the condition. And cigarette smoking has also been found to lead more severe bouts of the disease.

Treatment

There are several categories of drugs that can control inflammation caused by Crohn's disease:

  • Anti-inflammatory drugs: Drugs such as sulfasalazine (Azulfidine), mesalamine (Asacol®, Rowasa®), and corticosteroids are often the first-line of defense in the treatment of Crohn's disease.
  • Immune system suppressors: In addition to targeting your immune system, these drugs reduce inflammation. These immunosuppressants include asathioprine (Imuran®), infliximab (Remicade®), adalimumab (Humira®), certolizumab pegol (Cimzia®), methotrexate (Rheumatrex®), and cyclosporine (Gengraf®, Neoral®, Sandimmune®).
  • Antibiotics: Antibiotics can heal fistulas and abscesses. Some frequently prescribed antibiotics include metronidazole (Flagyl) and ciprofloxacin (Cipro®).

In addition to these drugs, there are many medications in clinical trials that help treat Crohn's disease.

If drug therapy doesn't work, your doctor may recommend surgery  to remove a damaged portion of your digestive tract to close fistulas, or remove scar tissue to relieve your symptoms.

Making some dietary and lifestyle adjustments may also bring relief:

  • Limit dairy consumption: Eliminating dairy products may help ease diarrhea, stomach pain, and gas.
  • Eat low-fat foods: Fatty foods can make diarrhea worse. Eliminating butter, margarine, cream sauc...

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